The AJAN affiliated field centres located and works with communities and the coordinating hub, situated in Nairobi. At the level of the field projects, Jesuits and their collaborators tackle the HIV epidemic under various angles. These comprise interventions that tackle HIV & AIDS at the various levels of those affected and infected. These responses include medical care for those infected, nutritional support, care for vulnerable and orphaned children, care for victims of gender-based violence, economic empowerment projects, psychosocial support, pastoral care and HIV prevention for the youth, youth education and empowerment. AJAN centres are found in more than 16 countries in Africa. The aim of their work is to mitigate the impact of AIDS epidemic, stem its progress, and promote life to the full among population plagued by the ongoing and emerging pandemics.
The second operational level is based at the secretariat, whose key function is the resource mobilization, capacity building, research, and coordination of the centres and common programs. The aim is to bind national working groups to step by step into an effective continental Jesuit Network with its own voice and ability to act in a coordinated fashion towards transformation of the communities they work for and with. The youth occupy a preponderant place in the network.